19.06.2019
Twi consecutive events will that take place on 17th and 18th July 2019.
The first event is the GRK1910 Workshop “Molecular dynamics simulations of GPCRs”, which will start on 17th July at 13:30 and end with a lecture of Prof. Hildebrand on the early afternoon of 18th July.
This lecture will also represent the start of the “Research Day” of the Emil-Fischer Graduate School, which takes place on the afternoon of the 18th July.
24.04.2019
"The GRK1910 workshop „Non-radioactive binding assays, held on June 11th at the University of Regensburg, was dedicated to methods used to investigate binding of bioactive small molecules to proteins such as receptors and enzymes, without using radiolabeled molecular tools. In the morning, guest docent Prof.
Kevin Burgess from Texas A&M University (Texas) gave a broad overview over the available approaches, and in the afternoon the participants put hands on in the lab, performed a BRET-based binding assay themselves, discussed the theoretical background and analyzed the data. The practical part was supervised by Lukas Grätz and Dr. Max Keller."
18.06.2018
The biannual Summer School in Medicinal Chemistry will be held from September 19th - September 21st, 2018 at the University of Regensburg.
It is co-organized by our research training group GRK1910 and is dedicated in memoriam Prof. Armin Buschauer who passed away too early last year. On Wednesday, September 19th, the summer school will start in the late afternoon with a memorial lecture in his honor followed by a get-together.
On Thursday and Friday (Sept 20th to 21st) the summer school will present a blend of interesting topics from medicinal chemistry including a poster session and a session with short oral presentations selected from the abstracts. There is no registration fee but registration is mandatory for logistic reasons.
Please save the date and register early as it will make the organization a lot easier.
Link for more Information and Registration:
15.06.2018
Prof. Klaus Kopka (DKFZ Heidelberg) will give a talk entitled
“The Heidelberg Series of Glu-ureido based PSMA tracers: Adaption of chemical structure to clinical indication"
Date: 13.07.2018, 12.15 p.m.
Venue: Auditorium, Translational Research Center (TRC) Schwabachanlage 12, Erlangen
02.05.2017
Prof. Kamil Baruch (Masaryk University Brno, CZ) will give two talks entitled
"Discovery of highly selective protein kinase inhibitors with the furo[3,2-b]pyridine core"
Date: 03.05.2017, 5.15 p.m.
Venue: UR, lecture hall H46
and
"Carbocyclic C-nucleosides: synthesis and potential use in modern biology"
Date: 04.05.2017, 12:00
Venue: UR, Seminar room 21.1.14
10.01.2017
Prof. Kjell Fuxe (Karolinska Institutet, Stockholm) will visit Erlangen on January 16th and 17th. His postdoc Dr. Dasiel Borroto-Escuela will give a talk entitled "On the existence of multiple A2A, D2R and Sigma1R allosteric receptor receptor interactions in Sigma1-D2R and A2A-D2R-Sigma1R heteroreceptor complexes: role in brain plasticity and cocaine".
Date: 17.01.2017, 5.15 p.m.
Venue: FAU, lecture hall Schuhstraße 19
10.01.2017
Prof. Nick Holliday (University of Nottingham) will give a talk entitled "Glowing pharmacology: insights from imaging GPCR ligand binding and dimerisation".
Subsequently, Prof. Carsten Hoffmann (Rudolf‐Virchow‐Zentrum, Würzburg) will talk about "G‐protein‐coupled receptor signaling in real time revealed by the use of optical probes".
Date: 26.01.2017, 3:00 p.m.
Venue: Lecture Hall H44, UR
14.07.2016
This year the retreat will be devided into two parts.
The PhD students and postdocs will meet on July 21st-22nd at Berghotel Sammüller in Neumarkt. At the same time, the PIs and coordinators meet at the Strandhotel Seehof in Langlaus
Retreat program
16.06.2016
The 8th Summer School "Medicinal Chemistry" organized and presented of the GRK1910 will take place in Regensburg on 21st-23rd September 2014.
For more informtion, see: Summer School 2016
20.04.2016
Prof. Dr. Bernhard Wünsch (Universität Münster) will give a talk at the FAU entitled "GluN2B selective NMDA receptor antagonists".
Date: 22.06.2016, 5.15 p.m.
Venue: FAU, lecture hall Schuhstraße 19
27.04.2016
Prof. Dr. Kevin Burgess (Texas A & M University) will give a talk entitled "Using EKO to sample conformational sweet-spots in peptidomimetic design".
Date: 02.06.2016, 5.15 p.m.
Venue: FAU, lecture hall Schuhstraße 19
On June 7/8, 2016, Kevin Burgess from the Texas A&M University will give a workshop for GRK1910 members.
The workshop will start on June 7th at 2 pm and will end on June 8th at 1 pm on the campus of the University of Regensburg, Biology building, room DE 2.121.
Dr. Irene Coin (University Leipzig) will give a talk entitled "Genetically incorporated chemical probes for GPCR studies".
Date: 01.06.2016, 5.15 p.m.
Venue: FAU, lecture hall Schuhstraße 19
The GLISTEN Erlangen 2016 conference is organised and funded by COST Action CM1207 together with the DFG Research Training Group GRK 1910.
Date: April 6th-8th, 2016.
26.10.2015
Prof. Dr. Takeaki Ozawa (University of Tokyo) will give a talk entitled "Luminescent sensors and optical switches for single cell analysis".
Date: 25.11.2015, 5.15 p.m.
Venue: FAU Erlangen-Nürnberg
13.01.2016
Seminar on "Good Scientific Practice" featuring
Dr. Brian Johnson (Wiley), who gives a talk entitled "Cases and Consequences of Scientific Misconduct – A Publisher’s View",
and
Prof. Christoph Meinel (Department of Philosophy and Humanities, UR)
Date: 10.02.2016, 3.00 p.m.
Venue: UR, lecture hass H46
03.03.2016
Prof. Dr. Takeaki Ozawa (University of Tokyo) will give a talk entitled "Luminescent sensors and optical switches for single cell analysis".
Date: 10.03.2016, 5.15 p.m.
Venue: UR, lecture hall DE 2.133
22.10.2015
Prof. Dr. Clemencia Pinilla (Torrey Pines Institute for Molecular Studies, San Diego) will give a talk entitled "Positional Scanning Libraries: Concepts, Identification of GPCR ligands and Elucidation of T cell specificity".
Date: 11.11.2015, 5.15 p.m.
Venue: FAU Erlangen-Nürnberg
14.10.2015
On Monday, November 9, GRK members will visit the High Throuput Screening facilities of Amgen (https://www.amgen.de/) in Regensburg in the morning, followed by a mini-workshop on label-free technologies in the afternoon.
On Tuesday, November 10, Dr. Clemencia Pinilla from the Torrey Pines Institute for Molecular Studies (http://www.tpims.org/our-scientists/california-team/clemencia-pinilla) will give a workshop on the use of synthetic combinatorial compound libraries for the de-novo identification of bioactive compounds, in Erlangen.
10.11.2015
A group of RTG fellows visited the high throughput screening facilities of Amgen Research GmbH in Regensburg.
According to official numbers the HTS lab screeens more than 15 million compounds per year for a variety of different targets. After an introductory talk describing Amgen's screening approaches and strategies, a tour through the HTS labs provided a vivid impression about lab automation and standardization. The day was completed by a mini-workshop on label-free approaches to monitor cell-based assays with special emphasis on GPCR as targets.
24.07.2015
At very summery temperatures above 30°C the second retreat of the Research Training Group took place on 22st-23nd July. After two great talks by Prof. Uwe Sonnewald and Prof. Torsten Kuwert the RTG members reported on their current projects, which formed the starting point for many fruitful and lively discussions.
To see some impressions of the retreat, please click on the picture below.
22.06.2015
The Research Day of the Emil Fischer Graduate Programme will take place on July 9th 2015.
Venue: Institute of Biochemistry, Fahrstrasse 17, Erlangen
19.05.2015
Prof. Dr. Mette Rosenkilde (University of Copenhagen) will give a talk entitled "Constitutive and biased signalling of chemokine receptors".
Date: 01.07.2015, 5.15 p.m.
Venue: FAU Erlangen-Nürnberg
Workshop for PhD students and postdocs.
Topic: Bioassays
Date: June 2nd-3rd 2015
Venue: FAU Erlangen-Nürnberg
Workshop for PhD students and postdocs.
Topic: GPCR Modeling
Date: May 19th 2015
Venue: FAU Erlangen-Nürnberg
Prof. Dr. Léon Ghosez (Institut Européen de Chimie et Biologie Bordeaux/Pessac – France) will give a talk entitled "Design and synthesis of natural-inspired scaffolds as an invaluable source of molecules of therapeutic interest".
Date: 06.05.2015, 5.15 p.m.
Venue: FAU Erlangen-Nürnberg
11.03.2015
Prof. Dr. Jens Carlsson (Stockholm University) will give a talk entitled "Successes and failures in structure-based discovery of GPCR ligands: Two steps forward, one step back".
Date: 22.04.2015, 5.15 p.m.
Venue: Lecture Hall, Schuhstrasse 19, FAU Erlangen-Nürnberg
20.10.2014
Dr. Mélanie Hall (Department of Chemistry, University of Graz, Austria) will give a talk on the "Development of Biocatalytic Tools for the Synthesis of Enantiopure Molecules".
Date: 29.10.2014, 5.15 p.m.
Venue: Lecture Hall H46, Organic Chemistry, University Regensburg
7th Summer School "Medicinal Chemistry"
Date: 17-19th September 2014
Venue: Universität Regensburg, Gebäude Physik, Hörsaal H36
Closed meeting for all RTG members
Date: July 21st-22nd 2014
Venue: Conference Hotel Behringers, Behringersmühle 23, 91327 Gößweinstein
17.02.2014
Current members of the GRK 1910 (click to enlarge)
The first workshop of our Research Training Group was held in Regensburg on February 13-14th.
Doctoral students, postdocs and supervisors met to get to know each other and to learn about all the starting research projects and teaching events. Additionally, Prof. Dr. Morten Grøtli (University of Gothenburg) gave a lecture about developing MEK and RET Inhibitors. Prof. Tim Clark introdoced the brand new web-based modeling server.
The assembly of graduates and postdocs elected Kilian Kuhn (UR) and Thorsten Schäfer (FAU) as Student representatives.
Some impressions of the workshop: (click to enter picture gallery)
22.11.2013
The first official event of the Research Training Group took place on November 21st. The FAU hosted the Kick-off Meeting featuring the following four invited speakers:
Prof. Dr. Rob Leurs (VU University Amsterdam)
Prof. Dr. Annette Beck-Sickinger (University Leipzig)
Prof. Dr. Christa Müller (University Bonn)
Prof. Dr. Elliott Richelson (Mayo Clinic, Jacksonville, Florida)
Pictures taken at the Kick-off Meeting: (click to enter image gallery)